What is it? Leukocyte Immunophenotyping is a laboratory test that identifies and characterizes different types of leukocytes (white blood cells) by analyzing specific CD (Cluster of Differentiation) markers on the surface of or inside the cells.
The analysis is usually performed using Flow Cytometry and is particularly important in the evaluation of hematological diseases and disorders of the immune system.
What does it analyze? Immunophenotyping can identify and determine the percentage of:
Depending on the purpose of the analysis, a broader panel of markers may be used.
When is it recommended? The test may be recommended for:
How is the test performed? The sample is usually collected from peripheral blood. In certain cases, a bone marrow sample may also be required. The cells are treated with specific antibodies conjugated to fluorochromes and analyzed using Flow Cytometry. This enables the identification of different cell populations based on their markers.
What do the results show? The results show the presence, percentage, and characteristics of different leukocyte populations. An abnormal profile may suggest the presence of a cell population that requires further evaluation.
An abnormal result does not automatically establish a diagnosis of leukemia or lymphoma. The results should be interpreted together with the complete blood count, clinical examination, and, when necessary, molecular or cytogenetic tests or a biopsy.
It is a test that identifies and characterizes different types of white blood cells (leukocytes) by analyzing specific CD markers on the cells.
Your doctor may recommend it to investigate changes in blood cells or to assist in the diagnosis and classification of leukemias, lymphomas, and disorders of the immune system.
A venous blood sample is usually collected. In certain cases, a bone marrow sample may also be required. The cells are analyzed using Flow Cytometry.
Depending on the panel, the following may be analyzed:
Yes. Immunophenotyping is one of the important tests used in the diagnosis and classification of leukemias and lymphomas, but the diagnosis is not based on this test alone.
The test can help identify and characterize cell populations that may be associated with lymphoma. Depending on the case, additional examinations may also be required.
An abnormal result may indicate the presence of a cell population with unusual characteristics. It does not automatically mean that the patient has cancer. The result should be interpreted by a hematologist together with other test results.
No. It may also be used to monitor the disease and evaluate treatment response in patients diagnosed with hematological diseases.
Yes. If there is a clinical indication, immunophenotyping can also be performed in children.
Blood sample collection takes only a few minutes.
Usually, no special preparation is required for blood collection. If other tests are being performed at the same time, follow the instructions provided by your doctor or laboratory.
The results should be interpreted by a hematologist or specialist physician, together with the complete blood count, symptoms, and other examinations.
Yes. Depending on the results, your doctor may recommend further tests, such as molecular or cytogenetic tests, genetic analyses, or a bone marrow examination.
