Panel Trombofilie

What is it?
The thrombophilia panel is a group of genetic and laboratory tests that assess the body's tendency to form blood clots (thrombi) more easily than normal.

This may lead to:

• Thrombosis (blood clots in the veins or arteries)
• Recurrent miscarriages
• Placental problems
• Complications during pregnancy

Many cases are genetic (inherited) and do not cause symptoms until a clinical problem occurs.

What does the Panel analyze?
The panel analyzes mutations in genes associated with the coagulation system and homocysteine metabolism.

Basic Panel – 6 factors
This panel includes the most common and clinically important mutations:

• Factor II (Prothrombin) – G20210A
• Factor V Leiden – G1691A (p.506Q)
• MTHFR – C677T
• MTHFR – A1298C
• PAI-1 – 4G/5G
• Factor XIII – p.V34L

Advanced Panel – 12 factors
For a more detailed and comprehensive analysis, the advanced panel includes:

• Factor II (Prothrombin) – G20210A
• Factor V Leiden – G1691A (p.506Q)
• MTHFR – C677T
• MTHFR – A1298C
• FV Cambridge
• FV H1299R
• PAI-1 – 4G/5G
• Factor XIII – p.V34L
• MTRR A66G
• MTR A2756G
• B-Fibrinogen – (-455G>A)
• FV Y1702C

Who is the test recommended for?

• Women with recurrent miscarriages
• Women with implantation failure (IVF)
• People with a history of thrombosis
• Pregnant women with complications
• People with a family history of thrombophilia

What are the benefits of the test?

• Early identification of genetic risk
• Potential for personalized treatment
• More closely monitored and safer pregnancy
• Prevention of serious complications

How is the test performed?

• A blood or saliva sample is collected
• The analysis is performed in a specialized laboratory
• The results are interpreted by specialist physicians